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Topoisomerase II inhibitor 13
CAS No. 451515-89-2
Topoisomerase II inhibitor 13( —— )
Catalog No. M36061 CAS No. 451515-89-2
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 46 | In Stock |
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| 10MG | 73 | In Stock |
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| 25MG | 121 | In Stock |
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| 50MG | 180 | In Stock |
|
| 100MG | 263 | In Stock |
|
| 200MG | 374 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTopoisomerase II inhibitor 13
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NoteResearch use only, not for human use.
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Brief DescriptionTopoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity.
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DescriptionTopoisomerase II inhibitor 13 is a topoisomerase II (Topo II) inhibitor. Topoisomerase II inhibitor 13 shows antiproliferative activity against several cancer cells. Topoisomerase II inhibitor 13 induces cancer cells apoptosis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number451515-89-2
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Formula Weight413.48
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Molecular FormulaC22H23N9
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 12.5 mg/mL (30.23 mM )
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SMILESNC1=C(C=2C(N1CCCN(CC)CC)=NC(C#N)=C(C#N)N2)C=3NC=4C(N3)=CC=CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li P H, et al. Synthesis and mechanism studies of 1, 3-benzoazolyl substituted pyrrolo [2, 3-b] pyrazine derivatives as nonintercalative topoisomerase II catalytic inhibitors. Journal of Medicinal Chemistry, 2016, 59(1): 238-252.
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